Zidane's side are still five points back and could see Barca extend that lead to eight when they face Villarreal on Sunday.
Los Blancos were having the opportunities, but Sevilla were enjoying plenty of the ball as they looked to hit back, and Carole had a low strike deflected just wide of the post in the 15th minute.
The 32-year-old Portuguese forward was magnificent as Real Madrid secured a Champions League and La Liga double last season. He was ranked seventh and the same metrics for Neymar's potential rise to the top can be used for the electric French talent.
However, normal service soon resumed and Marcelo's delicious delivery was nodded at goal by Benzema, but his header clipped the post and was promptly cleared. Either way, Cristiano will be the man spearheading the home attack; that's something no-one else has in their armoury.
Ronaldo squeezed a penalty beneath Rico after 31 minutes following a foolish handball from Jesus Navas, and the Portugal star played a key role in Madrid's fourth, winning back possession near the halfway line and releasing Kroos, who combined expertly with Lucas Vazquez before dispatching a composed finish.
"I have to thank my teammates, Real Madrid and the rest of the people who helped me to be in great shape throughout the season", said Ronaldo.
The 2007 winner, Kaka, was present for Thursday's Eiffel Tower gala, along with Real Madrid club president Florentino Perez and a number of former Blancos greats.
The first of those goals was enough for Ronaldo to reach another significant milestone.
Messi has an advantage in total titles with 55 but Ronaldo can close that gap next week as Real Madrid fly out to the Club World Cup in Abu Dhabi where he will be hoping for a team win and, perhaps, a Player of the Tournament award to boot.
"I'm not going to change after 15 years of my career".
Fans at the Santiago Bernabeu are beginning to show their frustration and - sharing a story of a fan who verbally abused him in an airport this week - the former Manchester United winger had a message for them. This type of amnesia, it really bothers me. But yes, obviously yes, because we love it and, try as we might, we cannot resist the storylines that the individuals create, the contrasting personalities to latch on to.